LS/VTEC with NOS or NOT?

Type R head
B18B bottom end
Skunk2 stage2 camshafts, retainers, and valve springs
Spoon 70mm TB
STR Fuel Rail, cam gears
CTR Pistons
GSR tranny
Cometic head gasket
Type R intake manifold
Comptech Race Header
Prelude Injectors

*Apexi V-AFC*


Now... I want to get NOS, but not sure if it's a good idea. As stated on the NOS catalog, "Do not use aftermarket chips or other devices that advance ignition timing as detonation may occur" So everyone that has NOS is using stock ECU? haha... no... Also, is compression too high for NOS? Does anyone have any experience? ideas? comments? etc? Let me know. Thanks!