Wow, that wasn't the reply I expected from grimey. NOt sure why...
For me, it's a philosophical thing (same reason I avoid fast food, alcohol and caffeine). Life is short, and anything I do to affect my "natural" body (whatever that means) limits my efforts to understand the "natural" world (whatever that is).
Oh, and I'm a wimp. Seriously, though, there's all kinds of excitement in one's unadulterated perception of the world if you're willing to find it.
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