this crossed my mind a few months ago. it would be an interesting swap, but you gotta remember, s2000s are RWD, civics are FWD...how would you convert that? that was the biggest snag i found. i would love to have this as a project car, but theres so many more things you could do for the money. when i posted this, one reply said that it would just be easiest to take a civic body and retro-fit it to an s2000 frame and engine.
sounds like a sweet project if ya got the time and cash...keep us posted if you attempt it